DURHAM, NC: September, 2008

ENTHALPY BOOSTS CAPACITY WITH LEADING-EDGE LIQUID HANDLING AUTOMATION – New Hamilton systems increase bioanalytical lab’s sample throughput.

Enthalpy Analytical, Inc.’s Bioanalytical Division has just added more Hamilton Microlab STAR™ workstations to its array of automated sample handling technology. Enthalpy’s new robotic systems allow greater volumes of drug discovery and development samples to be processed in less time, and with no compromises in precision. The equipment is validated for GLP (Good Laboratory Practice) projects.

The new Hamilton liquid handling systems are widely recognized for providing unprecedented increases in bioanalytical sample throughput. The workstations can be customized to accommodate a variety of sample processing methods, and increase capacity in conjunction with Enthalpy’s existing validated systems. The new systems also facilitate method transfers for Enthalpy’s research sponsors currently using the Hamilton technology.

“Enthalpy operates according to a business principle we call the ‘70 Percent Solution,’” explains Todd Grosshandler, Vice President. “That means we never run our lab at more than 70 percent of its maximum capacity so we can always maintain the speed and quality our clients expect.” Grosshandler added that Enthalpy is committed to never missing a deadline. The company’s new Hamilton workstations perform complex tasks in a fraction of the time required by traditional methods. For example, complex sample prep operations that previously required six to seven hours now take one hour.

Data analysis demonstrates that accuracy and consistency of the results obtained from the new automated sample preparation operations is equal or superior to samples prepared by hand or by previous technologies. Kendall Powell, Ph. D., a scientist at Enthalpy, has seen a huge boost in throughput efficiency. “By operating the Hamilton systems in conjunction with our Waters Acquity™ UPLCs, we’ve been able to remove significant rate limiting steps from our operations.”

Mike Allen, Director of Enthalpy’s Bioanalytical Division, has found the new automated systems useful across all aspects of pharmaceutical research projects. “We’re seeing significant increases in efficiency on large GLP projects, as well as discovery work,” he said.

Enthalpy Analytical, Inc. was founded in 1993 to provide analytical support for the environmental and pharmaceutical industries. Enthalpy today remains true to its mission of providing accurate, high-quality analytical services in a timely manner and for a reasonable cost.

Enthalpy's Bioanalytical Division began offering GLP-compliant LC/MS/MS bioanalytical services ten years after the company was founded and has since experienced significant growth. The division provides unusually responsive service featuring a single point of contact, quick turnaround times, and reliable, accurate results every time.

ABOUT ENTHALPY ANALYTICAL, INC.

Privately owned, Enthalpy Analytical was founded in 1993 to meet the marketplace need for fast, reliable analytical services. Enthalpy was the first lab in the Research Triangle to deploy the API 5000™. Enthalpy’s GLP-compliant LC/MS/MS Bioanalytical Division provides critical bioanalytical support at every stage of drug discovery and development.